HuLA immune(フライミューン)株式会社は、患者さんに笑顔になっていただくことを使命にした大阪大学発のバイオベンチャーです

HuLA immune(フライミューン株式会社)へはお気軽にお問い合わせ下さい


Key Technology

Key Technologyイメージ

Our novel medicines created by applying the “Neo-Self” theory advocated by Dr. Arase antibodies not only inhibit pathogenic signal transduction in vitro via both T cells and B cells involved in the onset and progression of autoimmune diseases, but also ameliorate pathological conditions of autoimmune diseases in several vivo mouse models. (

We are developing the medicines in several autoimmune diseases in response to unmet medical needs.

In regard to APS, we are also developing a new diagnostic agent applied by the ”Neo-Self” theory to solve diagnostic problems.


  • Arase, H. 2015. Rheumatoid Rescue of Misfolded Cellular Proteins by MHC Class II Molecules: A New Hypothesis for Autoimmune Diseases Adv. Immunol.
  • Arase, N., Arase, H. 2015. Cellular misfolded proteins rescued from degradation by MHC class II molecules are possible targets for autoimmune diseases. J.
    Biochem. 158:367-372.